Biochemical studies of toxic agents. 2. The metabolism of 2-naphthylamine and 2-acetamidonaphthalene
نویسندگان
چکیده
منابع مشابه
Biochemical Studies of Toxic Agents
The determination ofthe so-called 'ethereal sulphate content' of urine is a simple analytical procedure, and there are many reports in the literature which show that the administration of phenols to experimental animals is followed by an increased excretion ofethereal sulphates in the urine. On the other hand, because of the difficulties which have usually been encountered, relatively few ether...
متن کاملBiochemical Studies of Toxic Agents
1. The metabolism of cisand trans-acenaphthene-1,2-diol has been studied after the administration of these compounds to rats by subcutaneous injection and by stomach tube. 2. 1,8-Naphthalic acid has been isolated as its anhydride from the urine of the dosed animals. 3. A spectrophotometric method for the determination of free and conjugated 1,8-naphthalic acid in urine has been developed and ha...
متن کاملBiochemical studies of toxic agents; experiments with radioactive 2:3-dimercaptopropanol (British anti-lewisite).
During the period 1941-5, studies were conducted in this laboratory on the antidotal action of 2:3dimercaptopropanol (BAL, British Anti-Lewisite) and other thiols in arsenic poisoning; for review see Young (1946). The investigations were undertaken after receiving early reports of the work of Peters and his co-workers on the value of 2:3-dimercaptopropanol as an antidote to arsenic. In 1945 Pet...
متن کاملDesign and Synthesis of 2-Methyl and 2-Methyl-4-Nitro Imidazole Derivatives as Antifungal Agents
Two series (a and b) of N- substituted heteroaromatic compounds related to clotrimazole were synthesized. Imidazole ring of the clotrimazole was replaced by 2-methylimidazole in series a, and by 2-methyl-4-nitroimidazole in series b. O-cholortrityl moiety of clotrimazole was also replaced by trityl, mono or dimethoxy trityl. Chemical structures...
متن کامل70 Biochemical Studies of Toxic Agents
Baumann & Preusse (1879) and Jaff6 (1879) showed that the mercapturic acids which they isolated from the urine of dogs dosed with bromobenzene or chlorobenzene were formed by the decomposition of acid-labile compounds in the urine, and they believed that these precursors were derivatives of glucuronic acid. This work has recently been revised and extended as a result of the findings of Boyland,...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biochemical Journal
سال: 1950
ISSN: 0306-3283
DOI: 10.1042/bj0470170